Polynucleotides in Stuttgart – More Than a Trend, Real Skin Regeneration
The world of aesthetic treatments is full of short-lived trends, but some stand out because they truly deliver results. Polynucleotides, also known as salmon DNA or salmon sperm, belong to this new generation of treatments that genuinely improve skin quality from within. You may have already seen them on social media under names like “PN therapy,” “PN injections,” or as the “next-generation skin booster.”
But what’s behind them – and why are polynucleotides more than just a passing trend?
What Are Polynucleotides?
Polynucleotides are natural molecules made from DNA building blocks, specifically used in aesthetic medicine. Their greatest advantage? They work regeneratively and reparatively on the skin, supporting natural cellular renewal and restoring healthy skin function. Concretely, this means:
- Deep hydration – the skin is moisturized from within
- Fibroblast stimulation – more collagen & elastin production
- Improved microcirculation – skin looks healthier and fresher
- Protection against free radicals – fewer oxidative damages
The result isn’t a “puffed-up” or overfilled look, but a genuine improvement in skin quality from the inside out.
How Polynucleotides Became a Beauty Trend
Polynucleotides gained popularity through social media and celebrities openly sharing their treatments. On Instagram and other platforms, PN is celebrated as a “secret to youthful, glowing skin” – especially because results are subtle yet noticeable. Our patients appreciate that their skin simply looks rested and refreshed, but never overdone.
This natural outcome is exactly what has made polynucleotides evolve from a short-lived trend into a core element of modern skin regeneration.
The Science Behind It – Simply Explained
How does it actually work? Polynucleotides usually come from purified DNA building blocks from salmon or trout sperm. In the skin, these molecules act like tiny repair assistants — they support cellular regeneration, aid in tissue repair, and activate fibroblasts, our skin’s natural collagen factories.The skin is renewed from the inside: more moisture, more elasticity, fewer fine lines. At the same time, polynucleotides have strong anti-inflammatory and regenerative effects, making them particularly effective for delicate areas such as the under-eye and neck region.
Our patients benefit from natural, long-lasting skin improvement through personalized polynucleotide treatments tailored to the specific needs of the eye area, face, neck, and décolleté. The injections are placed in the superficial skin layers, where they stimulate regeneration and restore a healthy glow.
Who Is PN Therapy For?
Especially women and men aged 30–35+ benefit from polynucleotides when the skin shows early signs of fatigue, loss of elasticity, or fine lines. Typical treatment areas include:
✨ Under-eye area (dark circles, fine lines)
✨ Face & neck (fresher, plumper skin)
✨ Décolleté
✨ Hands
The under-eye area and neck respond particularly well to PN – areas where many other treatments are often less effective.
Polynucleotides at Aesthé Clinic Stuttgart
At Aesthé Clinic Stuttgart, we regularly use polynucleotides because we see how gently and effectively they regenerate the skin. Our approach is always: preserve natural beauty, strengthen skin health.
Doc. Lilly and our medical cosmetician Lida combine PN therapy individually with other treatments like radiofrequency microneedling, CO2 Laser or Endolift to achieve the best results for your skin. Most importantly, we take the time to analyze your skin thoroughly and create a personalized treatment plan.
After a detailed consultation with Doc. Lilly, the skin is carefully cleansed and prepared. The polynucleotides are then gently injected into the superficial skin layers, depending on the areas being treated. The session usually lasts 30–45 minutes, is gentle, precise, and tailored, so you feel comfortable throughout.
Another advantage: Downtime is minimal and manageable. Temporary redness, slight swelling, or small bruises may occur, so we recommend planning your treatment with upcoming activities in mind. These effects typically resolve within a few days, and the results are absolutely worth it.
Your Benefits with Polynucleotides
- Naturally radiant skin – never an overdone look
- Improved skin quality, visible & tangible
- Ideal for delicate areas such as the eyes and neck
- Long-lasting effects through genuine skin regeneration
Conclusion: More Than a Hype
Polynucleotides go beyond short-lived beauty trends, they represent the future of natural skin rejuvenation. They perfectly fit our philosophy: gentle treatments that strengthen your skin and highlight your natural beauty.
If you’d like to learn more, we warmly invite you to book a consultation at Aesthé Clinic Stuttgart and discover how polynucleotides can gently, safely, and effectively rejuvenate your skin from within.
